# NIH grant: Mobilizing Recovery Capital to Improve Outcomes for People living with HIV and Methamphetamine Use Disorder (1R34DA066379-01) — retained record

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[original source ↗](https://reporter.nih.gov/project-details/1R34DA066379-01)

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NIH grant 1R34DA066379-01: Mobilizing Recovery Capital to Improve Outcomes for People living with HIV and Methamphetamine Use Disorder
Institute: {'code': 'DA', 'abbreviation': 'NIDA', 'name': 'National Institute on Drug Abuse', 'admin_org_id': '12500072', 'admin_funding_url': ''}. PI: Sophia A. Hussen. Award: $210750.
Start: 2026-08-15T00:00:00.
PROJECT SUMMARY
Methamphetamine use is increasing in the United States, including among people living with HIV (PLH),
causing direct harms to individuals and threatening national progress towards ending the HIV epidemic.
Despite these trends, methamphetamine-focused recovery programs are relatively under-emphasized. Existing
interventions are primarily focused on individual-level behavior change without adequately addressing
interpersonal and community-level contributions to methamphetamine-related risk and resilience. Recovery
capital is a biopsychosocial framework which posits that people who use drugs possess assets and resources
(i.e., human, physical, social, and community capital) that can be leveraged to support recovery. However, this
strengths-based, multi-level approach is underutilized to date. We propose to develop and pilot test UPLIFT
(Uniting People, Leveraging Influence for Transformation), a novel intervention grounded in resilience and
recovery capital frameworks, to support PLH who use methamphetamine and their loved ones in recovery and
HIV care engagement. In Aim 1, we will use community-engaged processes to first conduct a qualitative study
to examine recovery capital, enrolling pairs of index participants and loved ones in qualitative interviews
incorporating elements of Photovoice. In Aim 2, we will work with a community participatory development team
to iteratively develop UPLIFT, drawing on these Aim 1 qualitative findings as well as our previously developed
social capital intervention for PLH, and using the ADAPT-ITT approach to intervention adaptation. In Aim 3, 2e
will pilot test and evaluate UPLIFT through a waitlist-control trial, examining acceptability, feasibility, and safety,
as well as preliminary measurement of substance use, HIV, and recovery capital outcomes. We will enroll 80
total participants in this pilot RCT, including 40 index participants (PLH who use or are in recovery from
methamphetamine) and 40 supportive loved ones. UPLIFT will be delivered by trained community health
workers with shared lived experience, and will incorporate weekly group sessions (enhancing social,
community, and human capital through psychoeducation, social support, and affirmation) and individualized
strengths-based case management sessions (enhancing physical and human capital through linkage to social
and health care services). The proposed research is highly significant because of its potential to develop a
novel, scalable intervention to support PLH who use methamphetamine and their loved ones through recovery,
addressing a pressing threat to individual and public health.
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