# NIH grant: T Cells in the Brain (TCB2027): Decoding T Cell Targets in Neurodegeneration (1R13AG104346-01) — retained record

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source: [us-gov-api](https://highsignal.app/data/us-gov-api) (us-gov-api:nih-reporter)  published 2026-09-05 00:00 ingested 2026-09-07 07:26

[original source ↗](https://reporter.nih.gov/project-details/1R13AG104346-01)

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NIH grant 1R13AG104346-01: T Cells in the Brain (TCB2027): Decoding T Cell Targets in Neurodegeneration
Institute: {'code': 'AG', 'abbreviation': 'NIA', 'name': 'National Institute on Aging', 'admin_org_id': '12500002', 'admin_funding_url': ''}. PI: Wassim  Elyaman. Award: $50000.
Start: 2026-09-05T00:00:00.
ABSTRACT
T cells are key contributors to neuroinflammation and neurodegeneration, yet identifying their targets and antigen specificities in human neurological disease remains a major challenge. Rapid advances in neuroimmunology, including single-cell multiomics, TCR repertoire sequencing, and antigen-discovery platforms, have begun to reshape our understanding of T cell biology in the CNS. Building on the success of TCB2024 and TCB2025, which each convened over 200 national and international attendees, the T Cells in the Brain series has established itself as the premier forum for integrating T cell biology with human neurodegeneration. These meetings generated new multi-institutional collaborations, fostered technology exchange among immunologists, neuropathologists, T cell engineers, and computational biologists, and supported several emerging joint grant applications and shared datasets. “T Cells in the Brain (TCB2027): Decoding T Cell Targets in Neurodegeneration” will advance this momentum by consolidating recent progress and promoting interdisciplinary discussion toward precision T-cell-based therapies. TCB remains committed to active efforts to engage trainees, and junior researchers. By uniting interdisciplinary expertise and strengthening collaborative networks, TCB2027 aims to accelerate the development of effective T cell-based interventions for neurodegenerative disorders.
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