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Wednesday 28 October 2026 Top stories today: - Fed seen holding rates despite hot inflation, with Dec. hike in focus - Anthropic reports early drug development gains with 6 partners - SK Hynix +11% as Q3 revenue +328% YoY, operating profit +632% - Google DeepMind’s Genie 4 debuts for interactive AI simulations - Physical Intelligence seeks $1B+ at ~$20B valuation 0. Data & Calendar All values as of 6 AM ET / 3 AM PT, other than S&P500 and NASDAQ close (4 PM ET / 1 PM PT). All times are ET. Listen to our AI-generated podcast summarizing today’s newsletter (beware of hallucinations) 1. Fed seen holding rates despite hot inflation, with Dec. hike in focus - Markets expect the Fed to hold rates at 3.75%-4.00%, though Fed Chair Warsh could face pressure to explain the decision. - Sep.: policymakers unanimously voted to raise rates to curb rising inflation. - 2 PM ET: FOMC rate decision. - 2:30 PM ET: Warsh speaks at a post-meeting press conference. Granola pulls together what you need before a meeting starts. Who you are talking to, what was agreed last time, what is still open. Read it in the two minutes before you join. *Sponsored. 3. Anthropic reports early drug development gains with 6 partners, acquires Mithril - One-person startup Mithril for two rare forms of muscular dystrophy. - Generate Biomedicines used Claude Code to redesign CAR T-cell therapies for cancer treatment. - Claude helped Divergence Labs generate ~35K antibody designs in a month for food allergy research. - Enveda used Claude to review 1,061 manufacturing pages, cutting review time by 89% and flagging 7 missed issues. Separately, Anthropic’s S-1 has implied a $40T+ annual TAM, topping SpaceX’s $28.5T estimate - Coresignal Monitors keeps your lead lists current. Turn any AI Data Search prompt into a standing monitor without touching the API. - Every week or sooner, we report new matching companies or employees, those that no longer match, and updated data records, by email or to your own webhook URL. - Pay for change, not repetition. Monitoring is free. Credits go only to the changed records you collect. *Sponsored. 5. SK Hynix +11% as Q3 revenue +328% YoY, operating profit +632%, both beat estimates - ₩104.6T (~$78.4B) in Q3 revenue, vs. ₩98.34T (~$73.7B) estimated. - SK Hynix plans ~$75B in 2026 shareholder returns, including $22B+ in dividends and $45B+ in buybacks. - Memory shortages will persist through 2030, SK Hynix predicted. micro1 pays U.S. businesses with at least 50 employees that are winding down to license their operational data for AI training. - Turn old internal documents, slack, email, codebase records, etc. into cashflow. - Help build simulated workplaces where AI learns to perform real business tasks. - Refer a company and earn up to $50,000 per successful referral. *Sponsored. 7. Google DeepMind’s Genie 4 debuts for interactive AI simulations - Powered by Gemini 3.8 Flash, Genie 4 can generate interactive experiences lasting ~2 minutes, vs. 1 minute for Genie 3. - Limited to trusted testers initially. - The model is pitched as a tool for film previsualization, game prototyping, and creating robot training scenarios. - Genie 4 is coming soon to Google AI Ultra subscribers, with a waitlist open for access through Project Genie.
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